Threshold of Toxicology Concern (TTC) Science Approach Document (SciAD) Public Comments Summary

June 2017

(PDF Format - 83 KB)

Comments were submitted during a 60-day public comment period for the Science Approach Document (SciAD) regarding the Threshold of Toxicology Concern (TTC) to be addressed as part of the Chemicals Management Plan.

A summary of comments and responses is included below, organized by topic:
MethodologyThe SciAD applies a pragmatic approach, compared to those applied in other regions; and the TCC approach is well recognized for food contact and impurities in pharmaceuticals, particularly in Europe.Noted.
MethodologyApplication of a conservative approach along with available values for limits of exposure seems to be reasonable. The robust and specific criteria assisted in selecting models and data most relevant to the 89 compounds considered as low concern.Noted.

Top of Page

Date modified: