Threshold of Toxicology Concern (TTC) Science Approach Document (SciAD) Public Comments Summary
June 2017
Comments were submitted during a 60-day public comment period for the Science Approach Document (SciAD) regarding the Threshold of Toxicology Concern (TTC) to be addressed as part of the Chemicals Management Plan.
| Topic | Comment | Response |
|---|---|---|
| Methodology | The SciAD applies a pragmatic approach, compared to those applied in other regions; and the TCC approach is well recognized for food contact and impurities in pharmaceuticals, particularly in Europe. | Noted. |
| Methodology | Application of a conservative approach along with available values for limits of exposure seems to be reasonable. The robust and specific criteria assisted in selecting models and data most relevant to the 89 compounds considered as low concern. | Noted. |
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