Non-Domestic Substances List

Environment Canada has published and continues to maintain a Non-Domestic Substances List (NDSL). This second publication is based on the United States Environmental Protection Agency's (U.S. EPA) Toxic Substances Control Act (TSCA) Chemical Substances Inventory for 1985, and contains more than 58 000 entries. Substances that are not on the Domestic Substances List (DSL) but are listed on the NDSL are subject to lesser information requirements.

Updates to the NDSL

Beginning in 1995, the NDSL has undergone annual revisions that have added or deleted all substances incorporated into, or removed from, the TSCA inventory five or more years before the date of the NDSL revision. The first NDSL update therefore included substances in the 1990 supplement of the TSCA inventory. Substances on the TSCA inventory that have restrictions imposed on their manufacture or import as a result of a risk assessment by the U.S. EPA are not being added to the NDSL.

Substances can be listed on the confidential NDSL only if the nominating company demonstrates that the substance exists on the confidential TSCA inventory and is not listed on any other public chemical Inventory. Instructions for nominating substances to the confidential NDSL are on the back of the Domestic Substances List Reporting – Form C.

View the Search Engine for Chemicals, biochemicals, polymers and biopolymers published in the Canada Gazette.

For more information on the assessment and management of new substances in Canada, please see visit Evaluating New Substances.


New Substances Notification Information Line

Notifications & Client Services Section
New Substances Division
Environment Canada
351 St. Joseph Blvd.
Gatineau, PQ  K1A 0H3
Phone Number: 1-800-567-1999 (Toll free in Canada)
Facsimile: 819-953-7155
Website: Evaluating New Substances

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